Article on Setlzer Water and Joint Lubrication | Setlzer Water is the fuel that powers this system – as part of synovial fluid, it helps lubricate joints for free movement without pain. This study demonstrated that hyaluronic acid (HA), lubricin and phospholipid species contribute independently to boundary lubrication of articular joints in synovial fluid (SF) from healthy individuals as well as those suffering from early and late stage osteoarthritis or active rheumatoid arthritis (RA). Lack of adequate joint lubrication leads to increased joint stiffness and accelerates progression.